ANGPTL4 (166-406) Recombinant Protein

CATALOG NUMBER: 96-028

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Pro 166 - Ser 406
Fusion Tag:
N-His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
27.9 kDa
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
50 mM MOPS, 100 mM NaCl, pH7.2 with 0.1% CHAPS
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
ANGPTL4
Additional Names:
ANGPTL4, ANGPTL2, ARP4, FIAF, HFARP, NL2, PGAR, pp1158, Angiopoietin like 4
Protein Accession Number:
NP_647475
Ncbi Gene Id Number:
51129
Background:
Angiopoietin-related protein 4 (ANGPTL4) is also known as Hepatic fibrinogen / angiopoietin - related protein (HFARP), ARP4, PGAR. ANGPTL4 contains one fibrinogen C-terminal domain. ANGPTL4 is a homooligomer , and the homooligomer undergoes proteolytic processing to release its carboxyl fibrinogen-like domain, which circulates as a monomer. The homooligomer unprocessed form is able to interact with the extracellular matrix. ANGPTL4 may act as a regulator of angiogenesis and modulate tumorigenesis. ANGPTL4 inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action.
Background Reference 1:
Yoon J.C., et al., 2000, Mol. Cell. Biol. 20:5343-5349.
Background Reference 2:
Ito Y., et al., 2003, Cancer Res. 63:6651-6657.
Background Reference 3:
Zhu H., et al., 2002, Zhonghua Zhong Liu Za Zhi 24:123-125.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-028

List Size:
0.1 mg

List Price:

$463.00

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