CD40 Recombinant Protein

CATALOG NUMBER: 96-086

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Glu 21 - Arg 193
Fusion Tag:
C-His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
20 kDa
Biological Activity:
Immobilized Human CD40, His Tag at 5ug/mL (100 uL/well) can bind Mouse CD40 Ligand, Fc Tag with a linear range of 2.6-16 ng/mL.
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
CD40
Additional Names:
CD40, Bp50, CDW40, MGC9013, TNFRSF5, p50
Protein Accession Number:
P25942-1
Ncbi Gene Id Number:
958
Background:
Tumor necrosis factor receptor superfamily member 5 (TNFRSF5) is also known as CD40, is a member of the TNF receptor superfamily. The expression of CD40 is diverse. TNFRSF5 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is the receptor for TNFSF5/CD40LG. Defects in CD40 are the cause of immunodeficiency with hyper-IgM type 3 (HIGM3).
Background Reference 1:
Ferrari S., et al., 2001, Proc. Natl. Acad. Sci. U.S.A. 98:12614-12619,
Background Reference 2:
Singh J., et al., 1998, Protein Sci. 7:1124-1135.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-086

List Size:
0.2 mg

List Price:

$577.00

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