SRBC Recombinant Protein

CATALOG NUMBER: 96-098

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Lys 25 - Asp 209
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
22.7 kDa
Biological Activity:
Immobilized Human CD58, Fc Tag at 5 ug/mL (100 uL/well) can bind Human CD2, His Tag with a linear range of 0.02-0.313 ug/mL.
Purity:
>98% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
CD2
Additional Names:
CD2, SRBC, LFA-2, T11
Protein Accession Number:
AAH33583
Ncbi Gene Id Number:
914
Background:
T-cell surface antigen CD2 is also known as Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5 and SRBC, is a single-pass type I membrane protein found on the surface of T cells and natural killer (NK) cells. CD2 is a member of the immunoglobulin superfamily. CD2 / SRBC contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD2 / SRBC interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3 / CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections.
Background Reference 1:
Wilkins A., et al., 2003, Curr Protein Pept Sci 4 (5): 367–73.
Background Reference 2:
Yang J., et al., 2001, Curr Protein Pept Sci 2 (1): 1–17.
Background Reference 3:
Bodian D.L., et al., 1994, Structure 2:755-766.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-098

List Size:
0.05 mg

List Price:

$626.00

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