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Human GITR, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%.
Human GITR, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%.

TNFRSF 18 Recombinant Protein

CATALOG NUMBER: 96-354

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Gln 26 - Glu 161
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
16.4 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human GITR, His Tag (Cat# 96-354) at 2 ug/mL (100 ul/well) can bind Human GITR Ligand, Fc Tag (Cat# GIL-H526a) with a linear range of 0.8-25 ng/mL.
Purity:
>92% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
TNFRSF18
Additional Names:
AITR, GITR, TNFRSF18, CD357
Protein Accession Number:
Q9Y5U5-1
Ncbi Gene Id Number:
8784
Background:
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Background Reference 1:
Gurney A.L., et al., 1999, Curr. Biol. 9:215-218.
Background Reference 2:
Park MS., et al., 2007, Yonsei Med J 48 (5): 839-46.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-354

List Size:
0.1 mg

List Price:

$515.00

Datasheet
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