HSP 90 alpha Recombinant Protein

CATALOG NUMBER: 96-395

Tested Applications:
WB
Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
Glu 535 - Asp 732
Fusion Tag:
N-GST Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
49.3 kDa
Purity:
>85% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
50 mM HEPES, pH7.0, with 150 mM NaCl
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
HSP90AA1
Additional Names:
HSP90AA1, HSP90A, HSP 86, HSP86, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2
Protein Accession Number:
NP_005339
Ncbi Gene Id Number:
3320
Background:
Heat shock protein HSP 90-alpha (HSP90AA1 or HSP90A) is also known as Heat shock 86 kDa (HSP 86 or HSP86), Renal carcinoma antigen NY-REN-38, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2, which belongs to the heat shock protein 90 family. HSP90AA1 undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. HSP90AA1 interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Background Reference 1:
Martinez-Ruiz A., et al., 2005, Proc. Natl. Acad. Sci. U.S.A. 102:8525-8530.
Background Reference 2:
Forsythe H.L., et al., 2001, J. Biol. Chem. 276:15571-15574.
Background Reference 3:
Yang J., et al., 2005, EMBO J. 24:1-10.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-395

List Size:
0.1 mg

List Price:

$463.00

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