Lipopolysaccharide Recombinant Protein

CATALOG NUMBER: 96-506

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Ala 26 - Val 481
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
52.8 kDa
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH 7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
LBP
Additional Names:
Lambda Chain Binding Protein, Lambda Binding Protein, LBP
Protein Accession Number:
P18428
Ncbi Gene Id Number:
3929
Background:
Lipopolysaccharide-binding protein (LBP),a member of the BPI/LBP/Plunc superfamily, BPI/LBP family, is detected in blood serum. LBP plays a role in the innate immune response. Alao,LBP can bind to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and act as an affinity enhancer for CD14, facilitating its association with LPS. Furthermore, LBP is able to promote the release of cytokines in response to bacterial lipopolysaccharide.
Background Reference 1:
Schumann R.R., et al., 1990, Science 249:1429-1431.
Background Reference 2:
Hubacek J.A., et al., 1997, Biochem. Biophys. Res. Commun. 236:427-430.
Background Reference 3:
Eckert J.K., et al., 2013, Immunity 39:647-660.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-506

List Size:
0.1 mg

List Price:

$540.00

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