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The purity of rh PIGR was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.
The purity of rh PIGR was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

Poly Ig receptor Recombinant Protein

CATALOG NUMBER: 96-627

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Lys 19 - Arg 638
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
68.7 kDa
Purity:
>98% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
PIGR
Additional Names:
PIGR, Poly-Ig receptor
Protein Accession Number:
AAI10495.1
Ncbi Gene Id Number:
5284
Background:
Polymeric immunoglobulin receptor (PIGR) is also known as Poly-Ig receptor, which can be cleaved into membrane secretory component (SC). PIGR is a type I transmembrane glycoprotein or a member of the immunoglobulin superfamily, and is synthesized by secretory epithelial cells and delivered to the basolateral plasma membrane where it can bind larger polymers of IgA (pIgA) and pentameric IgM. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
Background Reference 1:
Krajci P., et al., 1991, Hum. Genet. 87:642-648.
Background Reference 2:
Eiffert H., et al., 1984, Hoppe-Seyler's Z. Physiol. Chem. 365:1489-1495.
Background Reference 3:
Hughes G.J., et al., 1997, FEBS Lett. 410:443-446.
Background Reference 4:
Hamburger A.E., et al., 2004, Structure 12:1925-1935.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-627

List Size:
0.1 mg

List Price:

$463.00

Datasheet
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