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The purity of rh SCARB1 /SR-BI Fc Chimera was determined by DTT-reduced (+) and non-reduced (-) SDS-PAGE and staining overnight with Coomassie Blue.
The purity of rh SCARB1 /SR-BI Fc Chimera was determined by DTT-reduced (+) and non-reduced (-) SDS-PAGE and staining overnight with Coomassie Blue.

SCARB1 Recombinant Protein

CATALOG NUMBER: 96-673

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Pro 33 - Tyr 443
Fusion Tag:
C-Fc Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
72.6 kDa
Biological Activity:
Measured by its ability to bind recombinant Human ApoAI in a functional ELISA.
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
50 mM tris, 100 mM glycine, pH7.5
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
SCARB1
Additional Names:
SCARB1, CD36L1, SRB1, CLA-1, SR-BI, HDLQTL6
Protein Accession Number:
NP_005496.4
Ncbi Gene Id Number:
949
Background:
Scavenger receptor class B member 1 (SRB1) is also known as SR-BI, CD36 and LIMPII analogous 1 (CD36L1), CLA-1, is a member of the scavenger receptor family or CD36 family. CD36L1 is an integral membrane protein found in numerous cell types/tissues, including the liver and adrenal. SRB1 is receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. CLA-1 facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as high-density lipoprotein (HDL) and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. SCARB1 is, along with CD81, the receptor for the entry of the Hepatitis C virus glycoprotein E2 in liver cells, and binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. SRB1 plays an important role in the uptake of HDL cholesteryl ester.
Background Reference 1:
Acton S., et al., 1996, Science 271 (5248): 518–20.
Background Reference 2:
Duggan AE., et al., 2002, J. Exp. Zool. 292 (5): 430–4.
Background Reference 3:
Kapadia SB., et al., 2007, J. Virol. 81 (1): 374–83.
Background Reference 4:
Scarselli E., et al., 2002, EMBO J. 21:5017-5025.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-673

List Size:
0.05 mg

List Price:

$540.00

Datasheet
Shipping Info

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