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The purity of rh SERPINF1 / PEDF was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.
The purity of rh SERPINF1 / PEDF was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

Serpin F1 Recombinant Protein

CATALOG NUMBER: 96-679

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Gln 20 - Pro 418
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
45.2 kDa
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
SERPINF1
Additional Names:
SERPINF1, Serpin F1, PEDF, PIG35, EPC-1
Protein Accession Number:
NP_002606
Ncbi Gene Id Number:
5176
Background:
erpin F1 (SERPINF1) is also known as Pigment epithelium-derived factor (PEDF), Cell proliferation-inducing gene 35 protein (PIG35). Serpin F1 belongs to the serpin family. Serpin F1 is expressed in quiescent cells. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. Endothelial cell migration is inhibited by SERPINF1/ PEDF. PEDF / SERPINF1 suppresses retinal neovascularization and endothelial cell proliferation. PEDF is also responsible for apoptosis of endothelial cells either through the p38 MAPK pathway or through the FAS/FASL pathway. PEDF also displays neurotrophic functions.
Background Reference 1:
Duh EJ., et al., 2002, Invest Ophthalmol Vis Sci 43 (3): 821–9.
Background Reference 2:
Amaral J., et al., 2010, Invest Ophthalmol Vis Sci 51 (3): 1318–26.
Background Reference 3:
Chen L., et al., 2006, Biochem. Biophys. Res. Commun. 348 (4): 1288–95.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-679

List Size:
0.1 mg

List Price:

$515.00

Datasheet
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