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The purity of rh TFPI2 was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.
The purity of rh TFPI2 was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

TFPI2 Recombinant Protein

CATALOG NUMBER: 96-712

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Asp 23 - Lys 213
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
22.7 kDa
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
TFPI2
Additional Names:
TFPI2, PP5, REF1
Protein Accession Number:
NP_006519.1
Ncbi Gene Id Number:
7980
Background:
Tissue Factor Pathway Inhibitor 2 (TFPI­2) is also known as placental protein 5 (PP5) and retinal pigment epithelial cell factor 1 (REF­1), is a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). TFPI2 is highly abundant in the full-term placenta and widely expressed in umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy. TFPI­2 may play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa and has no effect on thrombin. Reduced synthesis of TFPI-2 has been related to numerous pathophysiological processes such as inflammation, angiogenesis, atherosclerosis, retinal degeneration and tumor growth / metastasis.
Background Reference 1:
Rao C.N., et al., 1995, Arch. Biochem. Biophys. 317:311-314.
Background Reference 2:
Tanaka Y., et al., 2004, Invest. Ophthalmol. Vis. Sci. 45:245.  
Background Reference 3:
Rollin J., et al., 2005, Br, J. Cancer 92:775. 

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-712

List Size:
0.05 mg

List Price:

$540.00

Datasheet
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