Vaccinia Virus B18R Recombinant Protein

CATALOG NUMBER: 97-072

Tested Applications:
ELISA, WB
Specifications
source-species:
HEK293 cells
Species:
Vaccinia Virus
source-species:
HEK293 cells
Recombinant Protein Sequence:
His 20 - Glu 351
Fusion Tag:
His Tag
Tested Applications:
ELISA, WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
40.3 kDa
Purity:
>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
B18R
Additional Names:
B18R
Protein Accession Number:
P25213
Ncbi Gene Id Number:
3707577
Background:
B18R is a type I interferon (IFN)-binding protein and it is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus, which contains two Ig-like C2-type domains and one Ig-like V-type domain. B18R exists in a soluble and a membrane-bound form. As a type I IFN receptor, B18R counteracts the antiviral effects of host IFN-alpha/beta. Also, B18R acts as a soluble IFN-alpha receptor and thus inhibits the interaction between host IFN-alpha and its receptor.
Background Reference 1:
Alcami A., et al., 2000, J. Virol. 74:11230-11239.
Background Reference 2:
Waibler Z., et al., 2009, J. Virol. 83:1563-1571.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

97-072

List Size:
0.05 mg

List Price:

$682.00

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