LIV-1 / SLC39A6 Recombinant Protein

CATALOG NUMBER: 11-144

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Phe 29 - Trp 325
Fusion Tag:
Fc Tag
Tested Applications:
WB
Application Note:
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.1 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Predicted Molecular Weight:
60.1 kDa
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
SLC39A6
Additional Names:
SLC39A6,LIV-1,ZIP6,Zinc transporter ZIP6,ZIP-6
Protein Accession Number:
XP_011524203.1
Ncbi Gene Id Number:
25800
Background:
LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.
Background Reference 1:
D L Manning, et al. Mol Cell Endocrinol. 1988. 59(3):205-12.
Background Reference 2:
Kathryn M Taylor, et al. Biochem J. 2003. 375(Pt 1):51-9.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

11-144

List Size:
0.1 mg

List Price:

$658.00

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