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Human SLAMF1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Human SLAMF1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

SLAMF1 / SLAM / CD150 Recombinant Protein

CATALOG NUMBER: 11-493

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Ala 21 - Pro 237
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.2 kDa. The protein migrates as 42-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Predicted Molecular Weight:
26.2 kDa
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
SLAMF1
Additional Names:
SLAMF1,CD150,CDw150,SLAM,IPO-3
Protein Accession Number:
NP_003028.1
Ncbi Gene Id Number:
6504
Background:
Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family, also known as CD150, is the prototypic member of the SLAM subfamily of the CD2 protein family.SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. SLAMF1-induced signal-transduction events in T-lymphocytes are different from those in B-cells. The type I transmembrane glycoprotein Signaling Lymphocytic Activation Molecule (SLAM).
Background Reference 1:
Cannons JLt, et al., 2011, Annu Rev Immunol., 29, 665-705.
Background Reference 2:
Jordan MA, et al., 2011, J Immunol., 186(7), 3953-65.
Background Reference 3:
Berger SB, et al., 2010, Nat Immunol., 11(10), 920-7.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

11-493

List Size:
0.1 mg

List Price:

$495.00

Datasheet
Shipping Info

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