PEDF Recombinant Protein

CATALOG NUMBER: 90-263

Specifications
source-species:
CHO cells
Species:
Human
source-species:
CHO cells
Recombinant Protein Sequence:
Human PEDF (aa 20-418) is fused at the C-terminus of to a DDDDK-tag.
Fusion Tag:
DDDDK Tag
Application Note:
This recombinant proteins is for research use only.
Purity:
>95% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
physical-state:
Lyophilized
Buffer:
Contains PBS. Reconstitute with 100 μl sterile distilled water.
Concentration:
0.1mg/ml after reconstitution.
Storage Conditions:
Stable for at least 6 months after receipt when stored at -20°C.
Ncbi Official Symbol:
SERPINF1
Additional Names:
Pigment Epithelium-derived Factor, Cell Proliferation-inducing Gene 35 Protein, EPC-1, Serpin F1
Protein Accession Number:
P36955
Protein Gi Number:
39725934
Ncbi Gene Id Number:
5176
Background:
Pigment epithelium-derived factor (PEDF) is a 47 kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and foetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

90-263

List Size:
10 ug

List Price:

$391.00

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