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IL-2 Recombinant Protein

CATALOG NUMBER: 90-464

Specifications
source-species:
CHO cells
Species:
Human
source-species:
CHO cells
Recombinant Protein Sequence:
The extracellular domain of human IL-2 (aa 21-153) is fused to the N-terminus of the Fc region of human IgG1.
Fusion Tag:
Fc Tag
Application Note:
This recombinant proteins is for research use only.
Purity:
>98% (SDS-PAGE).

Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
physical-state:
Lyophilized
Buffer:
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute in 50 μl sterile water. Add 1X PBS to the desired protein concentration.
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Ncbi Official Symbol:
IL2
Additional Names:
Interleukin-2, Aldesleukin
Protein Accession Number:
NP_000577
Protein Gi Number:
28178861
Ncbi Gene Id Number:
3558
Background:
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

90-464

List Size:
50 ug

List Price:

$365.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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