Deoxycytidine Kinase Recombinant Protein

CATALOG NUMBER: 92-064

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
Met1-Leu260
Fusion Tag:
N-6 His, T7 tag
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Predicted Molecular Weight:
34 kD
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
physical-state:
Liquid
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHClpH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Storage Conditions:
Store at -20°C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Ncbi Official Symbol:
DCK
Additional Names:
Deoxycytidine Kinase, dCK
Protein Accession Number:
P27707
Ncbi Gene Id Number:
1633
Background:
Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG), and deoxyadenosine (dA). DCK has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. In addition, DCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents. DCK is clinically important because of its relationship to drug resistance and sensitivity.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

92-064

List Size:
0.05 mg

List Price:

$515.00

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