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LIGHT Recombinant Protein

CATALOG NUMBER: 40-301

Specifications
source-species:
High-5 Insect cells
Species:
Human
source-species:
High-5 Insect cells
Recombinant Protein Sequence:
RLGEMVTRLP DGPAGSWEQL IQERRSHEVN PAAHLTGANS SLTGSGGPLL WETQLGLAFL RGLSYHDGAL VVTKAGYYYI YSKVQLGGVG CPLGLASTIT HGLYKRTPRY PEELELLVSQ QSPCGRATSS SRVWWDSSFL GGVVHLEAGE KVVVRVLDER LVRLRDGTRS YFGAFMV
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized LIGHT recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted LIGHT is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing LIGHT recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
TNFSF14
Additional Names:
LTg, TR2, CD258, HVEML, LIGHT, UNQ391/PRO726, Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, HVEM-L
Protein Accession Number:
NP_003798.2
Protein Gi Number:
25952144
Ncbi Gene Id Number:
8740
Background:
LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFκB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant human LIGHT has a calculated mass of 19.3 kDa containing 177 amino acid residues. Due to glycosylation LIGHT migrates between 20.0-22.5 kDa by SDS-PAGE under non-reducing conditions.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-301

List Size:
0.003 mg, 0.015 mg

List Price:

Price range: $199.00 through $305.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

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