BAFF Receptor Recombinant Protein

CATALOG NUMBER: 40-306

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG
Biological Activity:
Biological activity was determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED50 for this effect is 2.0 - 4.0 μg/mL in the presence of 1.0μg/mL of human soluble BAFF.
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized BAFF Receptor recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted BAFF Receptor is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing BAFF Receptor recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
TNFRSF13C
Additional Names:
BAFFR, CD268, CVID4, BAFF-R, BROMIX, prolixin, BAFFR, BR3, Tumor necrosis factor receptor superfamily member 13C, B-cell-activating factor receptor
Protein Accession Number:
NP_443177.1
Protein Gi Number:
16445027
Ncbi Gene Id Number:
115650
Background:
BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFFR is a 76 amino acid polypeptide (7.7 kDa) corresponding to the extracellular portion of the full BAFFR protein.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-306

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $199.00 through $305.00

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