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TWEAK Receptor Recombinant Protein

CATALOG NUMBER: 40-312

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
EQAPGTAPCS RGSSWSADLD KCMDCASCRA RPHSDFCLGC AAAPPAPFRL LWP
Biological Activity:
Biological activity was determined by its ability to inhibit TWEAK - induced weak cell death of HT29 cells. The expected ED50 for this effect is 1.0 - 3.0 μg/mL.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized TWEAK Receptor recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted TWEAK Receptor is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing TWEAK Receptor recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
TNFRSF12A
Additional Names:
FN14, CD266, TWEAKR, FN14, Tumor necrosis factor receptor superfamily member 12A, Fibroblast growth factor-inducible immediate-early response protein 14, FGF-inducible 14
Protein Accession Number:
NP_057723.1
Protein Gi Number:
7706186
Ncbi Gene Id Number:
51330
Background:
TWEAKR belongs to the TNF family of transmembrane proteins and contains a cytoplasmic "death domain", which can activated the cell's apoptotic machinery. It is expressed in the spleen, thymus, peripheral blood lymphocytes, colon, and small intestine. Signal transduction by TWEAKR can be activated by either the membrane anchored or the soluble TWEAK. Recombinant soluble TWEAKR is a 53 amino acid polypeptide (5.6 kDa) comprising the entire extracellular domain of the full length TWEAKR protein.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-312

List Size:
0.005 mg, 0.025 mg

List Price:

Price range: $199.00 through $305.00

Datasheet
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