Betacellulin Recombinant Protein

CATALOG NUMBER: 40-578

Specifications
source-species:
E. coli
Species:
Murine
source-species:
E. coli
Recombinant Protein Sequence:
DGNTTRTPET NGSLCGAPGE NCTGTTPRQK VKTHFSRCPK QYKHYCIHGR CRFVVDEQTP SCICEKGYFG ARCERVDLFY
Biological Activity:
Biological activity was determined by its ability to stimulate the proliferation of mouse Balb/3T3 cells. The expected ED50 is ≤ 0.01 ng/mL, corresponding to a specific activity of ≥ 1 x 108 units/mg. Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
physical-state:
Lyophilized
Storage Conditions:
The lyophilized Betacellulin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Betacellulin stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Betacellulin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
Btc
Additional Names:
Bcn, Bcn, Probetacellulin, BTC
Protein Accession Number:
NP_031594.1
Protein Gi Number:
6680812
Ncbi Gene Id Number:
12223
Background:
Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant murine Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-578

List Size:
0.005 mg, 0.02 mg

List Price:

Price range: $199.00 through $305.00

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