Midkine Recombinant Protein

CATALOG NUMBER: 40-581

Specifications
source-species:
E. coli
Species:
Murine
source-species:
E. coli
Recombinant Protein Sequence:
MVAKKKEKVK KGSECSEWTW GPCTPSSKDC GMGFREGTCG AQTQRVHCKV PCNWKKEFGA DCKYKFESWG ACDGSTGTKA RQGTLKKARY NAQCQETIRV TKPCTSKTKS KTKAKKGKGK D
Biological Activity:
Biological activity was determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/mL. Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
physical-state:
Lyophilized
Storage Conditions:
The lyophilized Midkine recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Midkine stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Midkine recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
Mdk
Additional Names:
MK, Mek, Mk, Midkine, Retinoic acid-induced differentiation factor, MK
Protein Accession Number:
NP_001012335.1
Protein Gi Number:
59894790
Ncbi Gene Id Number:
17242
Background:
Midkine and its functionally-related protein Pleiotrophin are heparin-binding neurotrophic factors that signal through the same receptor, known as anaplastic lymphoma kinase (ALK). MK plays an important regulatory role in epithelial-mesenchymal interactions during fetal development and in postnatal lung development. MK chemoattracts embryonic neurons, neutrophils and macrophages, and by signaling through the ALK receptor it exerts angiogenic, growth and survival activities during tumorgenesis. Recombinant murine Midkine is a 13.4 kDa protein containing 121 amino acid residues including five intra-molecular disulfide bonds.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-581

List Size:
0.005 mg, 0.02 mg

List Price:

Price range: $215.00 through $323.00

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