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IL-36RA Recombinant Protein

CATALOG NUMBER: 40-676

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
VLSGALCFRM KDSALKVLYL HNNQLLAGGL HAGKVIKGEE ISVVPNRWLD ASLSPVILGV QGGSQCLSCG VGQEPTLTLE PVNIMELYLG AKESKSFTFY RRDMGLTSSF ESAAYPGWFL CTVPEADQPV RLTQLPENGG WNAPITDFYF QQCD
Biological Activity:
Measured by its ability to inhibit secretion of IL-8 by A431 cells in the presence of IL-36γ.
Purity:
≥ 98% by SDS-PAGE gel and HPLC analyses.
physical-state:
Lyophilized
Storage Conditions:
The recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
IL36RN
Additional Names:
Interleukin-36RA, FIL1 delta, IL-1F5, IL-1HY1, IL-1L1, IL-1RP3, IL-1ra Homolog 1, IL-1 delta
Ncbi Gene Id Number:
26525
Background:
The IL-1 family is comprised of 11 structurally related ligands, including the recently re-named IL-36RA (IL-1F5), IL-36α (IL-1F6), IL-36β (IL-1F8), and IL-36γ (IL-1F9). The interaction of IL-36 ligands with the IL-1Rrp2 receptor (IL-1R6) can induce various activities, including dendritic cell maturation and activation. IL-36RA can antagonize the NF-κB signaling induced by either IL-36α, β or γ by binding to the IL-1Rrp2 receptor in a manner that prevents the initiation of functional signaling. Recombinant Human IL-36RA is an E. coli-derived 17 kDa protein containing 154 amino acid residues.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-676

List Size:
5 ug

List Price:

$217.00

Datasheet
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