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Western blot analysis of Unc93a in HeLa cell lysate with Unc93a antibody at (A) 0.5 and (B) 1 μg/mL.
Western blot analysis of Unc93a in HeLa cell lysate with Unc93a antibody at (A) 0.5 and (B) 1 μg/mL.
Trial Size

Unc93a Antibody

CATALOG NUMBER: 4551

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Unc93a antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human Unc93a.
The immunogen is located within the last 50 amino acids of Unc93a.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
Unc93a antibody can be used for the detection of Unc93a by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Specificity:
Two isoforms of Unc93a are known to exist. This antibody will not cross-react with Unc93b.
Positive Control 1:
Cat. No. 1201 - HeLa Cell Lysate
Purification:
Unc93a Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
Unc93a Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
Unc93a antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
UNC93A
Additional Names:
Unc93a Antibody: Unc-93A, dJ366N23.1, dJ366N23.2, Protein unc-93 homolog A, HmUnc-93A
Protein Accession Number:
AAH99718
Protein Gi Number:
71043465
Ncbi Gene Id Number:
54346
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Unc93a Antibody: Unc93a, a human homolog of the C. elegans Unc93 gene, was initially identified by the sequencing of chromosome 6q27 at D6S193 as loss at this region correlated with sporadic ovarian cancer. Further analysis however, showed no tumor suppressor role for Unc93a. Unlike Unc93b, another homolog of the C. elegans Unc93 gene that is crucial for Toll-like receptor (TLR) signaling, the function of Unc93a is unknown. It is expressed in testis, small intestine, spleen, prostate and ovary.
Background Reference 1:
Liu Y, Dodds P, Emilion G, et al. The human homolog of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer. BioMed Central Genetics2002; 3:20.
Background Reference 2:
Massey DC and Parkes M. Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease. Autophagy2007; 3:649-51.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

4551

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
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