Trial Size

PGCC1 Antibody

CATALOG NUMBER: 5309

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (92%)
Immunogen:
PGCC1 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human PGCC1.
The immunogen is located within the last 50 amino acids of PGCC1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
PGCC1 antibody can be used for detection of PGCC1 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.
Specificity:
This antibody will not cross-react with FAM120A.
Positive Control 1:
Cat. No. 1471 - Rat Thymus Tissue Lysate
Purification:
PGCC1 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
PGCC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
PGCC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FAM120B
Additional Names:
PGCC1 Antibody: CCPG, PGCC1, KIAA1838, dJ894D12.1, CCPG, Constitutive coactivator of peroxisome proliferator-activated receptor gamma, PPARG constitutive coactivator 1, Constitutive coactivator of PPAR-gamma
Protein Accession Number:
Q96EK7
Protein Gi Number:
74751843
Ncbi Gene Id Number:
84498
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PGCC1 Antibody: The transcription factor peroxisome proliferator-activated receptor gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.
Background Reference 1:
Berger J and Moller DE. The mechanisms of actions of PPARs. Annu. Rev. Med.2002; 53:409-35.
Background Reference 2:
Li D, Kang Q, and Wang D-M. Constitutive coactivator of peroxisome proliferator-activated receptor (PPARg), a novel coactivator of PPARg that promotes adipogenesis. Mol. Endocrin.2007; 21:2320-33.
Background Reference 3:
Holden S and Raymond FL. The human gene CXorf17 encodes a member of a novel family of putative transmembrane proteins: cDNA cloning and characterization of CXorf17 and its mouse ortholog orf34. Gene2003; 318:149-61.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

5309

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

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