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Western blot analysis of TMEM184B in rat lung tissue lysate with TMEM184B antibody at (A) 1 and (B) 2 μg/mL.
Immunohistochemistry of TMEM184B in human lung tissue with TMEM184B antibody at 5 μg/mL.
Immunofluorescence of TMEM184B in human lung tissue with TMEM184B antibody at 20 μg/mL.
Western blot analysis of TMEM184B in rat lung tissue lysate with TMEM184B antibody at (A) 1 and (B) 2 μg/mL.
Trial Size

TMEM184B Antibody

CATALOG NUMBER: 5683

Clonality:
Polyclonal
Tested Applications:
ELISA, IF, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Immunogen:
TMEM184B antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TMEM184B.
The immunogen is located within the last 50 amino acids of TMEM184B.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IF, IHC-P, WB
Application Note:
TMEM184B antibody can be used for detection of TMEM184B by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Positive Control 1:
Cat. No. 1462 - Rat Lung Tissue Lysate
Positive Control 2:
Cat. No. 10-101 - Human Lung Tissue Slide
Purification:
TMEM184B Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
TMEM184B Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
TMEM184B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TMEM184B
Additional Names:
TMEM184B Antibody: FM08, HS5O6A, C22orf5, PSEC0108, Transmembrane protein 184B, Putative MAPK-activating protein FM08
Protein Accession Number:
NP_036396
Protein Gi Number:
63259329
Ncbi Gene Id Number:
25829
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TMEM184B Antibody: TMEM184B, also known as C22orf5, is a 407 amino acid multi-pass membrane protein and represents a novel gene in the activation of the MAPK signaling pathway. The gene encoding TMEM184B maps to human chromosome 22; mutations in several of the genes in chromosome 22 are involved in the development of autism, schizophrenia, Phelan-McDermid syndrome and Neurofibromatosis type 2, suggesting that TMEM184B may play a role in these syndromes.
Background Reference 1:
Matsuda A, Suzuki Y, Honda G, et al. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. Oncogene2003; 22:3307-18.
Background Reference 2:
Dunham I, Shimizu N, Roe BA, et al. The DNA sequence of human chromosome 2. Nature1999; 402:489-495.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

5683

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

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