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Western blot analysis of NALP13 in K562 cell lysate with NALP13 antibody at 1 μg/mL.
Immunocytochemistry of NALP13 in K562 cells with NALP13 antibody at 2.5 μg/mL.
Immunofluorescence of NALP13 in K562 cells with NALP13 antibody at 20 μg/mL.
Western blot analysis of NALP13 in K562 cell lysate with NALP13 antibody at 1 μg/mL.
Trial Size

NALP13 Antibody

CATALOG NUMBER: 5973

Clonality:
Polyclonal
Tested Applications:
ELISA, ICC, IF, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
NALP13 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human NALP13.
The immunogen is located within amino acids 150 - 200 of NALP13.
Conjugate:
Unconjugated
Tested Applications:
ELISA, ICC, IF, WB
Application Note:
NALP13 antibody can be used for detection of NALP13 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Positive Control 1:
Cat. No. 1204 - K562 Cell Lysate
Positive Control 2:
Cat. No. 17-004 - K-562 Cell Slide
Purification:
NALP13 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
NALP13 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
NALP13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
NLRP13
Additional Names:
NALP13 Antibody: NOD14, PAN13, NALP13, CLR19.7, NOD14, NACHT, LRR and PYD domains-containing protein 13, Nucleotide-binding oligomerization domain protein 14
Protein Accession Number:
EAW72420
Protein Gi Number:
119592826
Ncbi Gene Id Number:
126204
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
NALP13 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP13 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP13, it has been suggested that it may be implicated in the activation of proinflammatory caspases via inflammasomes.
Background Reference 1:
Tschopp J, Martinon F, and Burns K. NALPs: a novel protein family involved in inflammation. Nat. Rev. Mol. Cell Biol.2003; 4:95-104.
Background Reference 2:
Tian X, Pascal G, and Monget P. Evolution and functional divergence of NLRP genes in mammalian reproductive system. BMC Evol. Biol.2009; 9:202.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

5973

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
Shipping Info

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