Trial Size

SLAMF9 Antibody

CATALOG NUMBER: 6181

Clonality:
Polyclonal
Tested Applications:
ELISA, IF, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
SLAMF9 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human SLAMF9.
The immunogen is located within the last 50 amino acids of SLAMF9.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IF, IHC-P, WB
Application Note:
SLAMF9 antibody can be used for detection of SLAMF9 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Specificity:
SLAMF9 antibody is predicted to not cross-react with other SLAM protein family members.
Positive Control 1:
Cat. No. 1405 - Mouse Kidney Tissue Lysate
Positive Control 2:
Cat. No. 10-401 - Human Kidney Tissue Slide
Purification:
SLAMF9 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
SLAMF9 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
SLAMF9 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SLAMF9
Additional Names:
SLAMF9 Antibody: CD2F10, CD84H1, SF2001, CD2F-10, CD84-H1, CD2F10, UNQ1938/PRO4421, SLAM family member 9, CD2 family member 10
Protein Accession Number:
NP_001139645
Protein Gi Number:
226342990
Ncbi Gene Id Number:
89886
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SLAMF9 Antibody: The SLAM (signalling lymphocyte activation molecule) family is a novel group of receptors on T cells in modulating the immune response. SLAMF9, also known as CD2F-10 or CD84 homolog, is a 289 amino acid type I transmembrane protein that shares 58% identity with the mouse protein. The SLAMF9 protein is predominantly expressed in hematopoietic tissues and contains an extracellular region with only two N-linked glycosylation sites, a 20-residue transmembrane region and a highly positively charged 30-residue cytoplasmic tail, suggesting a role for SLAMF9 as an adhesion molecule. SLAMF9 is thought to function in the immune response as a coreceptor for lymphocyte activation.
Background Reference 1:
Veillette A and Latour S. The SLAM family of immune-cell receptors. Curr. Opin. Immunol. 2003; 15:277-85.
Background Reference 2:
Veillette A. SLAM family receptors regulate immunity with and without SAP-related adaptors. J. Exp. Med. 2004; 199:1175-8.
Background Reference 3:
Fennelly JA, Tiwari B, Davis SJ, et al. CD2F-10: a new member of the CD2 subset of the immunoglobulin superfamily. Immunogenetics 2001; 53:599-602.
Background Reference 4:
Detre C, Keszei M, Romero X, et al. SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions. Semin. Immunopathol. 2010; 32:157-71.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

6181

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

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