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Western blot analysis of ApoA5 in human liver tissue lysate with ApoA5 antibody at 1 μg/mL .
Western blot analysis of ApoA5 in human liver tissue lysate with ApoA5 antibody at 1 μg/mL .
Trial Size

ApoA5 Antibody

CATALOG NUMBER: 6271

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Chicken, Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Chicken, Human
Immunogen:
ApoA5 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of chicken ApoA5.
The immunogen is located within the last 50 amino acids of ApoA5.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
ApoA5 antibody can be used for detection of ApoA5 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Positive Control 1:
Cat. No. 1304 - Human Liver Tissue Lysate
Purification:
ApoA5 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
ApoA5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
ApoA5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
APOA5
Additional Names:
ApoA5 Antibody:
Protein Accession Number:
XP_417939
Protein Gi Number:
118101989
Ncbi Gene Id Number:
419802
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ApoA5 Antibody: Apoliproprotein A-V is a protein coded by the APOA5 gene, which is highly expressed in the liver. This protein is responsible for binding to lipids in the liver and forming lipoproteins. In recent years, the gene has been used as a marker for measuring cardiovascular health as well as metabolic syndromes. The protein plays an important role in plasma triglyceride (lipid) regulation within the body. Although only expressed in the liver, APOA5 has functions both inside and outside of cells, as well as modulating triglyceride homeostasis in areas like the gut. Mutations in the APOA5 gene have up to 3 times the risk for the development of cardiovascular disease in association studies. Dietary studies support this lack of metabolic regulation by showing that any mutation in APOA5 will result in higher triglyceride levels than control groups when dieting.
Background Reference 1:
de Luis Roman et al. Nutrients 2022, 14(12): 2427.
Background Reference 2:
Jacob et al. BMC nephrology 2022, 23, 307.
Background Reference 3:
May-Zhang et al. Biochimica et biophysica acta (BBA) - Molecular and cell biology of lipids 2022, 1867 (9): 159185.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

6271

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
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