Trial Size

TRPV1 Antibody

CATALOG NUMBER: 7179

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Guinea pig: (81%), Mouse: (75%)
Immunogen:
Rabbit polyclonal TRPV1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TRPV1.
The immunogen is located within the last 50 amino acids of TRPV1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
TRPV1 antibody can be used for detection of TRPV1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Positive Control 1:
Cat. No. 1204 - K562 Cell Lysate
Predicted Molecular Weight:
Predicted: 92 kDa
Purification:
TRPV1 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
TRPV1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
TRPV1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Ncbi Official Symbol:
TRPV1
Additional Names:
TRPV1 Antibody: VR1, VR1, Transient receptor potential cation channel subfamily V member 1, Capsaicin receptor, TrpV1
Protein Accession Number:
NP_542437
Protein Gi Number:
74315354
Ncbi Gene Id Number:
7442
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TRPV1 Antibody: TRPV1 is a receptor for capsaicin, the main pungent ingredient in hot chili peppers, and elicits a sensation of burning pain by selectively activating sensory neurons. TRPV1 is a non-selective cation channel that is structurally related to members of the TRP family of ion channels such as TRPC3 and TRPC6. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo.
Background Reference 1:
Eid SR and Cortright DN. Transient receptor potential channels on sensory nerves. Handb. Exp. Pharmacol. 2009; 194:261-81.
Background Reference 2:
Minke B and Cook B. TRP channel proteins and signal transduction. Physiol. Rev. 2002; 82:429-72.
Background Reference 3:
Planells-Cases R, Valente P, Ferrer-Montiel A, et al. Complex regulation of TRPV1 and related thermo-TRPs: implications for therapeutic intervention. Adv. Exp. Med. Biol. 2011; 704:491-515.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

7179

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

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