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Immunohistochemistry of BMP15 in human prostate tissue with BMP15 antibody at 10 μg/mL
Immunohistochemistry of BMP15 in human prostate tissue with BMP15 antibody at 10 μg/mL
Trial Size

BMP15 Antibody

CATALOG NUMBER: 4739

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC-P
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse: (89%), Sheep: (83%), Bovine: (83%)
Immunogen:
Rabbit polyclonal BMP15 antibody was raised against an 18 amino acid peptide near the amino terminus of human BMP15.
The immunogen is located within amino acids 60 - 110 of BMP15.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC-P
Application Note:
BMP15 antibody can be used for detection of BMP15 by Western blot at 1 - 2 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.
Positive Control 1:
Cat. No. 10-635 - Human Prostate Tissue Slide
Predicted Molecular Weight:
43 kDa
Purification:
BMP15 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
BMP15 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
BMP15 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Ncbi Official Symbol:
BMP15
Additional Names:
BMP15 Antibody: ODG2, POF4, GDF9B, Bone morphogenetic protein 15, BMP-15
Protein Accession Number:
NP_005439
Protein Gi Number:
257743454
Ncbi Gene Id Number:
9210
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
BMP15 Antibody: BMP15, or GDF9B is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily that are involved in embryonic development and adult tissue homeostasis. BMP15 is expressed exclusively in the oocyte. It is an oocyte-specific growth/differentiation factor that may be involved in oocyte maturation and follicular development. Defects in BMP15 are the cause of ovarian dysgenesis type 2. BMP15 could be used as an oogenesis marker to track human amniotic fluid stem cells differentiation into the oocyte-like cells.
Background Reference 1:
Massague J. The transforming growth factor-beta family. Ann. Rev. Cell. Biol. 1990; 6:597-641
Background Reference 2:
Aaltonen J, Laitinen MP, Vuojolainen K, et al. Human growth differentiation factor 9 (GDF-9) and its novel homolog GDF-9B are expressed in oocytes during early foliculogenesis. J. Clin. Endocrinol. Metab. 1999; 84:2744-50.
Background Reference 3:
Laitinen M, Vuojolainen K, Jaatinen R, et al. A novel growth differentiation factor-9 (GDF-9) related factor is coexpressed with GDF-9 in mouse oocytes during folliculogenesis. Mech. Dev. 1998; 78:135-40.
Background Reference 4:
Galloway SM, Gregan SM, Wilson T et al. Bmp15 mutations and ovarian function. Mol. Cell Endocrinol. 2002; 191:15-8

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

4739

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
Shipping Info

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