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Western blot analysis of CNRIP1 in human brain tissue lysate with CNRIP1 antibody at 1 μg/mL.
Immunohistochemistry of CNRIP1 in rat brain tissue with CNRIP1 antibody at 2.5 μg/ml.
Immunofluorescence of CNRIP1 in rat brain tissue with CNRIP1 antibody at 20 μg/ml.
Western blot analysis of CNRIP1 in human brain tissue lysate with CNRIP1 antibody at 1 μg/mL.
Trial Size

CNRIP1 Antibody

CATALOG NUMBER: 7303

Clonality:
Polyclonal
Tested Applications:
ELISA, IF, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (93%)
Immunogen:
CNRIP1 antibody was raised against a 15 amino acid peptide near the center of human CNRIP1.
The immunogen is located within amino acids 50 - 100 of CNRIP1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IF, IHC-P, WB
Application Note:
CNRIP1 antibody can be used for detection of CNRIP1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Specificity:
At least two isoforms of CNRIP1 are known to exist; this antibody will detect both isoforms.
Positive Control 1:
Cat. No. 1303 - Human Brain Tissue Lysate
Predicted Molecular Weight:
Predicted: 18 kDa
Observed: 16 kDa
Purification:
CNRIP1 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
CNRIP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
CNRIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Ncbi Official Symbol:
CNRIP1
Additional Names:
CNRIP1 Antibody: CRIP1, C2orf32, CB1 cannabinoid receptor-interacting protein 1, CRIP-1
Protein Accession Number:
NP_056278
Protein Gi Number:
24308071
Ncbi Gene Id Number:
25927
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CNRIP1 Antibody: The CNRIP1 (cannabinoid receptor interacting protein 1) protein is a G-protein coupled receptor which interacts with the C-terminal tail of cannabinoid receptor 1 (CB1) and is thought to play a role in synaptic plasticity, analgesia, appetite, and neuroprotection. One isoform of CNRIP1, CNRIP1a, modulates the constitutive CB1 receptor activity in the central nervous system (CNS), while the role of the shorter isoform CNRIP1b is yet unknown. CNRIP1 has been suggested as a potential target for CNS drug discovery.
Background Reference 1:
Niehaus JL, Liu Y, Wallis KT, et al. CB1 cannabinoid receptor activity is modulated by the cannabinoid receptor interacting protein CRIP 1a. Mol. Pharmacol. 2007; 72:1557-66.
Background Reference 2:
Smith TH, Sim-Selley LJ, and Selley DE. Cannabinoid CB1 receptor-interacting proteins: novel targets for central nervous system drug discovery. Br. J. Pharm. 2010; 160:454-66.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

7303

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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