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Western blot analysis of TFPI in rat small intestine tissue lysate with TFPI antibody at 1 μg/mL.
Immunohistochemistry of TFPI in rat small intestine tissue with TFPI antibody at 5 μg/mL.
Immunofluorescence of TFPI in rat small intestine tissue with TFPI antibody at 20 μg/mL.
Western blot analysis of TFPI in rat small intestine tissue lysate with TFPI antibody at 1 μg/mL.
Trial Size

TFPI Antibody

CATALOG NUMBER: 7441

Clonality:
Polyclonal
Tested Applications:
ELISA, IF, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Homology:
Predicted species reactivity based on immunogen sequence: Rabbit: (92%)
Immunogen:
TFPI antibody was raised against a 13 amino acid peptide near the amino terminus of human TFPI.
The immunogen is located within amino acids 70 - 120 of TFPI.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IF, IHC-P, WB
Application Note:
TFPI antibody can be used for detection of TFPI by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Specificity:
TFPI antibody is human, mouse and rat reactive. At least two isoforms of TFPI are known to exist; this antibody will detect both isoforms.
Positive Control 1:
Cat. No. 1468 - Rat Small Intestine Tissue Lysate
Predicted Molecular Weight:
Predicted: 33 kDa
Observed: 30 kDa
Purification:
TFPI Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
TFPI Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
TFPI antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Ncbi Official Symbol:
TFPI
Additional Names:
TFPI Antibody: EPI, TFI, LACI, TFPI1, Tissue factor pathway inhibitor, Extrinsic pathway inhibitor, TFPI
Protein Accession Number:
NP_006278
Protein Gi Number:
5454114
Ncbi Gene Id Number:
7035
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TFPI Antibody: Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation (1). TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop (1).
Background Reference 1:
Broze GJ Jr and Girard TJ. Tissue factor pathway inhibitor: structure-function. Front. Biosci. 17:262-80.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

7441

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
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