ANGPT1 Antibody

CATALOG NUMBER: 55-185

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Pig, Bovine
Immunogen:
This ANGPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the C-terminal region of human ANGPT1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:2000
Predicted Molecular Weight:
58 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ANGPT1
Additional Names:
Angiopoietin-1, ANG-1, ANGPT1, KIAA0003
Protein Accession Number:
Q15389
Protein Gi Number:
12229574
Ncbi Gene Id Number:
284
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Angiopoietins are proteins with important roles invascular development and angiogenesis. All angiopoietins bind withsimilar affinity to an endothelial cell-specific tyrosine-proteinkinase receptor. The protein encoded by this gene is a secretedglycoprotein that activates the receptor by inducing its tyrosinephosphorylation. It plays a critical role in mediating reciprocalinteractions between the endothelium and surrounding matrix andmesenchyme. The protein also contributes to blood vessel maturationand stability, and may be involved in early development of theheart.
Background Reference 1:
Fang, X., et al. J. Biol. Chem. 285(34):26211-26222(2010)
Background Reference 2:
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Background Reference 3:
Choe, J.Y., et al. Joint Bone Spine 77(4):340-344(2010)
Background Reference 4:
Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-185

List Size:
400 ul

List Price:

$495.00

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