PDE7B Antibody

CATALOG NUMBER: 55-329

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PDE7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 421-450 amino acids from the C-terminal region of human PDE7B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
52 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PDE7B
Additional Names:
cAMP-specific 3',5'-cyclic phosphodiesterase 7B, PDE7B
Protein Accession Number:
Q9NP56
Protein Gi Number:
13626185
Ncbi Gene Id Number:
27115
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The 3',5'-cyclic nucleotides cAMP and cGMP function assecond messengers in a wide variety of signal transductionpathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs)catalyze the hydrolysis of cAMP and cGMP to the corresponding5'-monophosphates and provide a mechanism to downregulate cAMP andcGMP signaling. This gene encodes a cAMP-specificphosphodiesterase, a member of the cyclic nucleotidephosphodiesterase family.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Kestenbaum, B., et al. J. Am. Soc. Nephrol. 21(7):1223-1232(2010)
Background Reference 3:
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Background Reference 4:
Ikeda, M., et al. Biol. Psychiatry 67(3):263-269(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-329

List Size:
400 ul

List Price:

$495.00

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