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Western blot analysis in A2058 cell line and mouse brain tissue lysates (35ug/lane).
Western blot analysis in A2058 cell line and mouse brain tissue lysates (35ug/lane).

LZTS1 Antibody

CATALOG NUMBER: 56-831

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This LZTS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-105 amino acids from the N-terminal region of human LZTS1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
67 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LZTS1
Additional Names:
Leucine zipper putative tumor suppressor 1, F37/esophageal cancer-related gene-coding leucine-zipper motif, Fez1, LZTS1, FEZ1
Protein Accession Number:
Q9Y250
Protein Gi Number:
46396556
Ncbi Gene Id Number:
11178
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a tumor suppressor protein that isubiquitously expressed in normal tissues. In uveal melanomas,expression of this protein is silenced in rapidly metastasizing andmetastatic tumor cells but has normal expression in slowlymetastasizing or nonmetastasizing tumor cells. This protein mayhave a role in cell-cycle control by interacting with theCdk1/cyclinB1 complex. This gene is located on chromosomal region8p22. Loss of heterozygosity (LOH) in the 8p arm is a commoncharacteristic of many types of cancer.
Background Reference 1:
Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 2:
Chattopadhyay, I., et al. Mutat. Res. 696(2):130-138(2010)
Background Reference 3:
Califano, D., et al. J. Cell. Physiol. 222(2):382-386(2010)
Background Reference 4:
Shyn, S.I., et al. Mol. Psychiatry (2009) In press :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-831

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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