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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
DUSP9 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

DUSP9 Antibody

CATALOG NUMBER: 57-334

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This DUSP9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-329 amino acids from the C-terminal region of human DUSP9.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
42 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DUSP9
Additional Names:
Dual specificity protein phosphatase 9, Mitogen-activated protein kinase phosphatase 4, MAP kinase phosphatase 4, MKP-4, DUSP9, MKP4
Protein Accession Number:
Q99956
Protein Gi Number:
3913541
Ncbi Gene Id Number:
1852
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of the dualspecificity protein phosphatase subfamily. These phosphatasesinactivate their target kinases by dephosphorylating both thephosphoserine/threonine and phosphotyrosine residues. Theynegatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associatedwith cellular proliferation and differentiation. Different membersof the family of dual specificity phosphatases show distinctsubstrate specificities for various MAP kinases, different tissuedistribution and subcellular localization, and different modes ofinducibility of their expression by extracellular stimuli. Thisgene product shows selectivity for members of the ERK family of MAPkinases, is expressed only in placenta, kidney, and fetal liver,and is localized to the cytoplasm and nucleus. [provided byRefSeq].
Background Reference 1:
Voight, B.F., et al. Nat. Genet. 42(7):579-589(2010)
Background Reference 2:
Liu, Y., et al. Cancer Res. 67(22):10711-10719(2007)
Background Reference 3:
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Background Reference 4:
Muda, M., et al. J. Biol. Chem. 272(8):5141-5151(1997)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-334

List Size:
400 ul

List Price:

$495.00

Datasheet
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