Mouse Irak4 Antibody

CATALOG NUMBER: 57-510

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This Mouse Irak4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-449 amino acids from the C-terminal region of mouse Irak4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
51 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
Irak4
Additional Names:
Interleukin-1 receptor-associated kinase 4, IRAK-4, Irak4
Protein Accession Number:
Q8R4K2
Ncbi Gene Id Number:
266632
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Irak4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1 (By similarity).
Background Reference 1:
Erdman, L.K., et al. J. Immunol. 183(10):6452-6459(2009)
Background Reference 2:
Maekawa, Y., et al. Circulation 120(14):1401-1414(2009)
Background Reference 3:
Bauernfeind, F.G., et al. J. Immunol. 183(2):787-791(2009)
Background Reference 4:
Staschke, K.A., et al. J. Immunol. 183(1):568-577(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-510

List Size:
400 ul

List Price:

$495.00

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