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Western blot analysis in MCF-7 cell line lysates (35ug/lane).
Western blot analysis in MCF-7 cell line lysates (35ug/lane).

PRKRIR Antibody

CATALOG NUMBER: 58-044

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PRKRIR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the N-terminal region of human PRKRIR.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
88 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PRKRIR
Additional Names:
52 kDa repressor of the inhibitor of the protein kinase, p52rIPK, 58 kDa interferon-induced protein kinase-interacting protein, p58IPK-interacting protein, Death-associated protein 4, THAP domain-containing protein 0, PRKRIR, DAP4, P52RIPK, THAP0
Protein Accession Number:
O43422
Ncbi Gene Id Number:
5612
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth.
Background Reference 1:
Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
Background Reference 2:
Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
Background Reference 3:
Lee, J.H., et al. KoreanGastroenterol 42(6):484-495(2003)
Background Reference 4:
Lin, Y., et al. J. Biol. Chem. 277(50):47991-48001(2002)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-044

List Size:
400 ul

List Price:

$495.00

Datasheet
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