PMP22 Antibody

CATALOG NUMBER: 58-253

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PMP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from human PMP22.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
18 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PMP22
Additional Names:
Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, GAS-3, PMP22, GAS3
Protein Accession Number:
Q01453
Protein Gi Number:
266803
Ncbi Gene Id Number:
5376
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Kohl, B., et al. Am. J. Pathol. 176(3):1390-1399(2010) Kabzinska, D., et al. J. Appl. Genet. 51(2):203-209(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Stangler Herodez, S., et al. J. Int. Med. Res. 37(5):1626-1631(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-253

List Size:
400 ul

List Price:

$495.00

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