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Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).
Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).

ACTR1A Antibody

CATALOG NUMBER: 58-272

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Rat
Immunogen:
This ACTR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the Central region of human ACTR1A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
43 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ACTR1A
Additional Names:
Alpha-centractin, Centractin, ARP1, Actin-RPV, Centrosome-associated actin homolog, ACTR1A, CTRN1
Protein Accession Number:
P61163
Protein Gi Number:
47117651
Ncbi Gene Id Number:
10121
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a 42.6 kD subunit of dynactin, amacromolecular complex consisting of 10-11 subunits ranging in sizefrom 22 to 150 kD. Dynactin binds to both microtubules andcytoplasmic dynein. It is involved in a diverse array of cellularfunctions, including ER-to-Golgi transport, the centripetalmovement of lysosomes and endosomes, spindle formation, chromosomemovement, nuclear positioning, and axonogenesis. This subunit ispresent in 8-13 copies per dynactin molecule, and is the mostabundant molecule in the dynactin complex. It is an actin-relatedprotein, and is approximately 60% identical at the amino acid levelto conventional actin.
Background Reference 1:
Sugarbaker, D.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(9):3521-3526(2008)
Background Reference 2:
Petretti, C., et al. EMBO Rep. 7(4):418-424(2006)
Background Reference 3:
Casenghi, M., et al. Dev. Cell 5(1):113-125(2003)
Background Reference 4:
Carew, J.A., et al. J. Thromb. Haemost. 1(6):1220-1227(2003)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-272

List Size:
400 ul

List Price:

$495.00

Datasheet
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