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Western blot analysis in Hela cell line lysates (35ug/lane).
Western blot analysis in Hela cell line lysates (35ug/lane).

BPNT1 Antibody

CATALOG NUMBER: 58-554

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This BPNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-305 amino acids from the C-terminal region of human BPNT1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
33 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
BPNT1
Additional Names:
3'(2'),5'-bisphosphate nucleotidase 1, Bisphosphate 3'-nucleotidase 1, PAP-inositol 1,4-phosphatase, PIP, BPNT1
Protein Accession Number:
O95861
Ncbi Gene Id Number:
10380
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
BPNT1, also called bisphosphate 3-prime-nucleotidase, orBPntase, is a member of a magnesium-dependent phosphomonoesterasefamily. Lithium, a major drug used to treat manic depression, actsas an uncompetitive inhibitor of BPntase. The predicted humanprotein is 92% identical to mouse BPntase. BPntase's physiologicrole in nucleotide metabolism may be regulated by inositolsignaling pathways. The inhibition of human BPntase may account forlithium-induced nephrotoxicity.
Background Reference 1:
Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
Background Reference 2:
Spiegelberg, B.D., et al. J. Biol. Chem. 274(19):13619-13628(1999)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-554

List Size:
400 ul

List Price:

$495.00

Datasheet
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