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Western blot analysis in HL-60 cell line lysates (35ug/lane).
Western blot analysis in HL-60 cell line lysates (35ug/lane).

CLK2 Antibody

CATALOG NUMBER: 58-679

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This CLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the Central region of human CLK2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
60 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CLK2
Additional Names:
Dual specificity protein kinase CLK2, CDC-like kinase 2, CLK2
Protein Accession Number:
P49760
Protein Gi Number:
1705919
Ncbi Gene Id Number:
1196
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the CLK family of dualspecificity protein kinases. CLK family members have been shown tointeract with, and phosphorylate, serine- and arginine-rich (SR)proteins of the spliceosomal complex, which is a part of theregulatory mechanism that enables the SR proteins to control RNAsplicing. Note that this gene is distinct from TELO2 gene(GeneID:9894), which shares CLK2 and hCLK2 symbol aliases in commonwith this gene, but encodes a protein that is involved in telomerelength regulation.
Background Reference 1:
Nam, S.Y., et al. J. Biol. Chem. 285(41):31157-31163(2010)
Background Reference 2:
Eisenreich, A., et al. Circ. Res. 104(5):589-599(2009)
Background Reference 3:
Rendtlew Danielsen, J.M., et al. J. Biol. Chem. 284(7):4140-4147(2009)
Background Reference 4:
Castle, J.C., et al. Nat. Genet. 40(12):1416-1425(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-679

List Size:
400 ul

List Price:

$495.00

Datasheet
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