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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

ARAP2 Antibody

CATALOG NUMBER: 58-826

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ARAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-93 amino acids from the N-terminal region of human ARAP2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
193 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ARAP2
Additional Names:
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2, Centaurin-delta-1, Cnt-d1, Protein PARX, ARAP2, CENTD1, KIAA0580
Protein Accession Number:
Q8WZ64
Protein Gi Number:
308153629
Ncbi Gene Id Number:
116984
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene contains ARF-GAP,RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homologydomains. The protein is a phosphatidylinositol(3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, butit lacks the predicted catalytic arginine in the RHO-GAP domain anddoes not have RHO-GAP activity. The protein associates with focaladhesions and functions downstream of RhoA to regulate focaladhesion dynamics.
Background Reference 1:
Gavicherla, B., et al. Infect. Immun. 78(11):4532-4541(2010)
Background Reference 2:
Liu, C., et al. Mol. Med. 14 (9-10), 575-581 (2008) :
Background Reference 3:
Yoon, H.Y., et al. J. Cell. Sci. 119 (PT 22), 4650-4666 (2006) :
Background Reference 4:
Olsen, J.V., et al. Cell 127(3):635-648(2006)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-826

List Size:
400 ul

List Price:

$495.00

Datasheet
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