IL23R Antibody

CATALOG NUMBER: 58-876

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This IL23R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the C-terminal region of human IL23R.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
72 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
IL23R
Additional Names:
Interleukin-23 receptor, IL-23 receptor, IL-23R, IL23R
Protein Accession Number:
Q5VWK5
Protein Gi Number:
311033431
Ncbi Gene Id Number:
149233
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a subunit of thereceptor for IL23A/IL23. This protein pairs with the receptormolecule IL12RB1/IL12Rbeta1, and both are required for IL23Asignaling. This protein associates constitutively with Janus kinase2 (JAK2), and also binds to transcription activator STAT3 in aligand-dependent manner.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Chen, J., et al. Mol. Carcinog. 49(10):862-868(2010)
Background Reference 3:
Mizuki, N., et al. Nat. Genet. 42(8):703-706(2010)
Background Reference 4:
Remmers, E.F., et al. Nat. Genet. 42(8):698-702(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-876

List Size:
400 ul

List Price:

$495.00

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