AGFG2 Antibody

CATALOG NUMBER: 59-494

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This AGFG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-130 amino acids from the Central region of human AGFG2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
49 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
AGFG2
Additional Names:
Arf-GAP domain and FG repeat-containing protein 2, HIV-1 Rev-binding protein-like protein, Rev/Rex activation domain-binding protein related, RAB-R, AGFG2, HRBL, RABR
Protein Accession Number:
O95081
Ncbi Gene Id Number:
3268
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of the HIV-1 Rev binding protein(HRB) family and encodes a protein with one Arf-GAP zinc fingerdomain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF)motifs. This protein interacts with Eps15 homology (EH) domains andplays a role in the Rev export pathway, which mediates thenucleocytoplasmic transfer of proteins and RNAs. Alternativelyspliced transcript variants have been described, but theirbiological validity has not been determined. The 3' UTR of thisgene contains an insulin receptor substrate 3-like pseudogene.
Background Reference 1:
Doria, M., et al. J. Cell Biol. 147(7):1379-1384(1999)
Background Reference 2:
Glockner, G., et al. Genome Res. 8(10):1060-1073(1998)
Background Reference 3:
Salcini, A.E., et al. Genes Dev. 11(17):2239-2249(1997)
Background Reference 4:
Wong, W.T., et al. Proc. Natl. Acad. Sci. U.S.A. 92(21):9530-9534(1995)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-494

List Size:
400 ul

List Price:

$495.00

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