ABCC9 Antibody

CATALOG NUMBER: 59-820

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This ABCC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-669 amino acids from the Central region of human ABCC9.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
174 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ABCC9
Additional Names:
ATP-binding cassette sub-family C member 9, Sulfonylurea receptor 2, ABCC9, SUR2
Protein Accession Number:
O60706
Ncbi Gene Id Number:
10060
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of thesuperfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- andintra-cellular membranes. ABC genes are divided into seven distinctsubfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). Thisprotein is a member of the MRP subfamily which is involved inmulti-drug resistance. This protein is thought to formATP-sensitive potassium channels in cardiac, skeletal, and vascularand non-vascular smooth muscle. Protein structure suggests a roleas the drug-binding channel-modulating subunit of theextrapancreatic ATP-sensitive potassium channels. No disease hasbeen associated with this gene thus far. Alternative splicing ofthis gene results in several products, two of which result fromdifferential usage of two terminal exons and one of which resultsfrom exon deletion.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010)
Background Reference 3:
Ellis, J.A., et al. Physiol. Genomics 40(3):184-188(2010)
Background Reference 4:
Kim, S.J., et al. Biochem. Biophys. Res. Commun. 391(1):974-978(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-820

List Size:
400 ul

List Price:

$495.00

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