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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

ALG8 Antibody

CATALOG NUMBER: 59-956

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This ALG8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-41 amino acids from the N-terminal region of human ALG8.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
60 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ALG8
Additional Names:
Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase, Asparagine-linked glycosylation protein 8 homolog, Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase, Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase, ALG8
Protein Accession Number:
Q9BVK2
Protein Gi Number:
143811361
Ncbi Gene Id Number:
79053
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the ALG6/ALG8glucosyltransferase family. The encoded protein catalyzes theaddition of the second glucose residue to the lipid-linkedoligosaccharide precursor for N-linked glycosylation of proteins.Mutations in this gene have been associated with congenitaldisorder of glycosylation type Ih (CDG-Ih). Alternatively splicedtranscript variants encoding different isoforms have beenidentified.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Stolting, T., et al. Mol. Genet. Metab. 98(3):305-309(2009)
Background Reference 3:
Jaeken, J., et al. Curr. Opin. Pediatr. 16(4):434-439(2004)
Background Reference 4:
Schollen, E., et al. J. Med. Genet. 41(7):550-556(2004)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-956

List Size:
400 ul

List Price:

$495.00

Datasheet
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