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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ALDOB antibody detected the ALDOB protein (arrow).
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ALDOB antibody detected the ALDOB protein (arrow).

ALDOB Antibody

CATALOG NUMBER: 60-153

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit, Rat
Immunogen:
This ALDOB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human ALDOB.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
39 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ALDOB
Additional Names:
Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB
Protein Accession Number:
P05062
Protein Gi Number:
113611
Ncbi Gene Id Number:
229
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is atetrameric glycolytic enzyme that catalyzes the reversibleconversion of fructose-1,6-bisphosphate to glyceraldehyde3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3aldolase isozymes which are distinguished by their electrophoreticand catalytic properties. Differences indicate that aldolases A, B,and C are distinct proteins, the products of a family of related'housekeeping' genes exhibiting developmentally regulatedexpression of the different isozymes. The developing embryoproduces aldolase A, which is produced in even greater amounts inadult muscle where it can be as much as 5% of total cellularprotein. In adult liver, kidney and intestine, aldolase Aexpression is repressed and aldolase B is produced. In brain andother nervous tissue, aldolase A and C are expressed about equally.There is a high degree of homology between aldolase A and C.Defects in ALDOB cause hereditary fructose intolerance. [providedby RefSeq].
Background Reference 1:
Bouteldja, N., et al. J. Inherit. Metab. Dis. 33(2):105-112(2010)
Background Reference 2:
Coffee, E.M., et al. J. Inherit. Metab. Dis. 33(1):33-42(2010)
Background Reference 3:
Segat, L., et al. J. Gastroenterol. Hepatol. 24(12):1840-1846(2009)
Background Reference 4:
Davit-Spraul, A., et al. Mol. Genet. Metab. 94(4):443-447(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-153

List Size:
400 ul

List Price:

$495.00

Datasheet
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