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Western blot analysis in A549 cell line lysates (35ug/lane).
Western blot analysis in A549 cell line lysates (35ug/lane).

XRCC4 Antibody

CATALOG NUMBER: 60-188

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This XRCC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human XRCC4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
38 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
XRCC4
Additional Names:
DNA repair protein XRCC4, X-ray repair cross-complementing protein 4, XRCC4
Protein Accession Number:
Q13426
Protein Gi Number:
44888352
Ncbi Gene Id Number:
7518
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene functions together withDNA ligase IV and the DNA-dependent protein kinase in the repair ofDNA double-strand break by non-homologous end joining and thecompletion of V(D)J recombination events. The non-homologousend-joining pathway is required both for normal development and forsuppression of tumors. This gene functionally complements XR-1Chinese hamster ovary cell mutant, which is impaired in DNAdouble-strand breaks produced by ionizing radiation and restrictionenzymes. Alternative transcription initiation and alternativesplicing generates several transcript variants. [provided byRefSeq].
Background Reference 1:
Gomes, B.C., et al. Oncol. Rep. 24(4):1079-1085(2010)
Background Reference 2:
Liu, Y., et al. Carcinogenesis 31(10):1762-1769(2010)
Background Reference 3:
Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)
Background Reference 4:
Liu, N., et al. Wei Sheng Yan Jiu 39(4):407-411(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-188

List Size:
400 ul

List Price:

$495.00

Datasheet
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