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Western blot analysis in A549 cell line lysates (35ug/lane).
Western blot analysis in A549 cell line lysates (35ug/lane).

SIRPB1 Antibody

CATALOG NUMBER: 60-449

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SIRPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-134 amino acids from the Central region of human SIRPB1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
43 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SIRPB1
Additional Names:
Signal-regulatory protein beta-1, SIRP-beta-1, CD172 antigen-like family member B, CD172b, SIRPB1
Protein Accession Number:
O00241
Ncbi Gene Id Number:
10326
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of thesignal-regulatory-protein (SIRP) family, and also belongs to theimmunoglobulin superfamily. SIRP family members are receptor-typetransmembrane glycoproteins known to be involved in the negativeregulation of receptor tyrosine kinase-coupled signaling processes.This protein was found to interact with TYROBP/DAP12, a proteinbearing immunoreceptor tyrosine-based activation motifs. Thisprotein was also reported to participate in the recruitment oftyrosine kinase SYK. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
Background Reference 1:
Gaikwad, S., et al. Am. J. Pathol. 175(6):2528-2539(2009)
Background Reference 2:
Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
Background Reference 3:
Martins-de-Souza, D., et al.Neural Transm 116(3):275-289(2009)
Background Reference 4:
Lamesch, P., et al. Genomics 89(3):307-315(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-449

List Size:
400 ul

List Price:

$495.00

Datasheet
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